The latest weight loss craze could also help people control their drinking.
Semaglutide treatments such as Ozempic and Wegovy have been shown to reduce the symptoms of alcohol use disorder (AUD), according to a study published in The Journal of Clinical Psychiatry on Nov. 27.
The collaborative study from The University of Oklahoma (OU) and Oklahoma State University (OSU) found a “significant and noteworthy decrease” in the Alcohol Use Disorders Identification Test (AUDIT) scores of six patients who were receiving semaglutide treatment for weight loss.
Lead study author Dr. Jesse Richards, Director of Obesity Medicine and Assistant Professor of Medicine at the OU-TU School of Community Medicine, said the study was inspired by his conversation with Dr. Kyle Simmons, Professor of Pharmacology and Physiology at the OSU Center for Health Sciences.
“I had been hearing from a significant number of patients that their alcohol intake was spontaneously decreasing while they were on the medication,” Richards told Fox News Digital.
As a bariatric surgery clinic employee, Richards noted that it’s standard to screen patients for alcohol use.
At the clinic, a number of patients tested positive for alcohol consumption, sometimes in concerning amounts.
Later, while on semaglutide medication, they reported reduced alcohol intake.
One of Richards’ patients, who previously drank large amounts of alcohol, shared a new inability to drink more than two cans of beer now because it “just doesn’t sound good.”
Research has shown that this effect is “mediated through adjustments in the reward pathway in the brain,” he said.
“The GLP-1s are actually modifying dopamine, decreasing the craving and decreasing the motivation to acquire things in that compulsive intake category.”
The most surprising takeaway from the study, Richards said, was that the same significant treatment response was seen even at very low doses.
(Fox News)
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