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Moderna releases data on “Breakthrough” cases

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According to the data, which Moderna released Wednesday, a “study shows lower risk of breakthrough infection in participants vaccinated more recently (median 8 months after first dose) than participants vaccinated last year (median 13 months after first dose).”

A Moderna trial conducted over the summer, labeled Phase 3 COVE Study, revealed that “88 breakthrough cases of COVID-19 occurred in the more recently vaccinated group (49.0 cases per 1000 person-years) compared to 162 cases in the group vaccinated last year (77.1 cases per 1000 person-years).”

Across both groups, Moderna highlighted that “only 19 severe cases were observed.” While there was a “numerical trend toward a lower rate of severe cases in the groups vaccinated more recently.” Moderna insisted that the number of cases was low enough that the trend was “not significant.”The research found that those who were vaccinated earlier on had a 50% higher rate of symptomatic breakthrough cases during the months of July and August compared to those who had received the vaccination later.

In a statement issued along with the data, Moderna CEO Stéphane Bancel insisted that the data “supports the need for a booster” shot.

“It is promising to see clinical and real-world evidence adding to the growing body of data on the effectiveness of the Moderna COVID-19 vaccine,” Bancel said of the unpublished analysis. (Fox)

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